Tin in PDB 3kwy: Crystal Structure of Rxralpha Ligand Binding Domain in Complex with Triphenyltin and A Coactivator Fragment

The structure of Crystal Structure of Rxralpha Ligand Binding Domain in Complex with Triphenyltin and A Coactivator Fragment, PDB code: 3kwy was solved by A.Le Maire, W.Bourguet, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	28.09 / 2.30
Space group	P 43 21 2
Cell size a, b, c (Å), α, β, γ (°)	64.635, 64.635, 113.589, 90.00, 90.00, 90.00
R / Rfree (%)	18.3 / 24.4

The binding sites of Tin atom in the Crystal Structure of Rxralpha Ligand Binding Domain in Complex with Triphenyltin and A Coactivator Fragment (pdb code 3kwy). This binding sites where shown within 5.0 Angstroms radius around Tin atom.
In total only one binding site of Tin was determined in the Crystal Structure of Rxralpha Ligand Binding Domain in Complex with Triphenyltin and A Coactivator Fragment, PDB code: 3kwy:

Tin binding site 1 out of 1 in the Crystal Structure of Rxralpha Ligand Binding Domain in Complex with Triphenyltin and A Coactivator Fragment


Mono view


Stereo pair view

A full contact list of Tin with other atoms in the Sn binding site number 1 of Crystal Structure of Rxralpha Ligand Binding Domain in Complex with Triphenyltin and A Coactivator Fragment within 5.0Å range: probe atom residue distance (Å) B Occ A:Sn1 b:24.6 occ:1.00 SN7 A:T9T1 0.0 24.6 1.0 C8 A:T9T1 2.1 24.5 1.0 C14 A:T9T1 2.1 24.5 1.0 C1 A:T9T1 2.1 25.2 1.0 SG A:CYS432 2.5 27.9 1.0 C11 A:T9T1 3.0 25.5 1.0 C19 A:T9T1 3.0 25.7 1.0 C16 A:T9T1 3.0 25.6 1.0 C13 A:T9T1 3.0 25.9 1.0 C2 A:T9T1 3.0 26.1 1.0 C3 A:T9T1 3.0 25.2 1.0 CB A:CYS432 3.3 27.8 1.0 CA A:CYS432 4.2 27.8 1.0 CD1 A:ILE345 4.3 24.3 0.5 C9 A:T9T1 4.3 24.9 1.0 C18 A:T9T1 4.3 26.7 1.0 C15 A:T9T1 4.3 27.9 1.0 C12 A:T9T1 4.4 23.6 1.0 C4 A:T9T1 4.4 26.1 1.0 C5 A:T9T1 4.4 25.0 1.0 CZ A:PHE313 4.9 23.9 1.0 C10 A:T9T1 4.9 23.9 1.0 C17 A:T9T1 4.9 27.1 1.0 C6 A:T9T1 4.9 24.5 1.0 CG2 A:ILE268 4.9 33.3 1.0

A.Le Maire, W.Bourguet, P.Balaguer. A Structural View of Nuclear Hormone Receptor: Endocrine Disruptor Interactions. Cell.Mol.Life Sci. V. 67 1219 2010.
ISSN: ISSN 1420-682X
PubMed: 20063036
DOI: 10.1007/S00018-009-0249-2